Brand Name : OMNIPLEX
Generic Name : Vitamin B-complex with vitamin C
Preparation : Capsule
Pharmacological Category : Vitamin Supplement
Composition
Thiamine HCl IP (Vit. B1) : 10.0 mg
Riboflavin IP (Vit. B2) : 10.0 mg
Niacinamide IP (Vit. B3) : 50.0 mg
Calcium Pantothenate IP (Vit. B5) : 15.0 mg
Pyridoxine HCl IP (Vit. B6) : 3.0 mg
Cyanocobalamine IP (Vit. B12) : 10.0 mcg
Ascorbic Acid (Vit. C) : 100.0 mg
Mechanism of Action (MOA)
OMNIPLEX has combined actions of all contained vitamins.
Thiamine (Vitamin B1) is essential coenzyme for carbohydrate metabolism and branched chain amino acids in the form of thiamine pyrophosphate also known as cocarboxylase.
Riboflavin (Vitamin B2) is involved in oxidation-reduction reactions in metabolic pathways and in energy production via the respiratory chain as essential coenzymes i.e. flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
Niacin (Vitamin B3) is the precursor to nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP). These coenzymes are involved in electron transfer reactions in the respiratory chain.
Calcium Pantothenate (Vitamin B5) is a component of coenzyme A, which is essential in the metabolism of carbohydrate, fat and protein.
Pyridoxine (Vitamin B6) is mainly involved in amino acid metabolism as a co-enzyme, but is also involved in carbohydrate and fat metabolism. Vitamin B6 is also required for the formation of haemoglobin.
Cyanocobalamin (Vitamin B12) is used in the body in the two forms i.e. methylcobalamin and 5-deoxyadenosyl cobalamin. Methylcobalamin acts as a cofactor during conversion of the amino acid homocysteine into methionine. Methionine in turn is required for DNA methylation. 5-Deoxyadenosyl cobalamin is a cofactor needed by the enzyme that converts L-methylmalonyl-CoA to succinyl-CoA. This conversion is an important step in the extraction of energy from proteins and fats. Furthermore, succinyl CoA is necessary for the production of hemoglobin.
Ascorbic acid (Vitamin C) is an electron donor essential for the synthesis of collagen and intercellular material. Vitamin C reduces gastric cancer risk, protects low-density lipoproteins against oxidation, stabilizes folate in food and in plasma, thus preventing anemia to occur, promotes absorption of iron by chelation or simply by maintaining the iron in the reduced form, promotes wound healing.
Indication and Dosage
Dietary / Nutritional Supplement : One capsule of OMNIPLEX once daily or as directed
Side Effects
Diarrhoea, abdominal pain, constipation, bright yellow discoloration of urine, dark stools, nausea, vomiting
Contraindication
Hypersensitivity
Pregnancy Category : A
Presentation
OMNIPLEX : A box of 20 blisters, each blister of 10 capsules
